Vascular Surgery Research    
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Khalil Lab

Principal Investigator
The main focus of the Khalil Laboratory of the Division of Vascular and Endovascular Surgery is to study the cellular mechanisms of vascular tone under physiological conditions and the changes in these mechanisms in pathological conditions such as coronary artery disease, salt-sensitive hypertension, abdominal aortic aneurysm, varicose veins and other chronic vascular diseases. Projects include investigation of endothelium-dependent mechanisms of vascular relaxation, Ca2+-dependent and Ca2+-independent mechanisms of vascular contraction, role of protein kinases and phosphatases in vascular smooth muscle contraction, mechanisms of gender-specific differences in vascular tone, role of endothelin in salt-sensitive hypertension, and cellular mechanisms responsible for vascular aneurysm formation, varicose veins and other inflammatory vascular disorders.
Wei Li, MD, PhD Student, Research Fellow
Marc Q. Mazzuca, PhD, Research Fellow  


       To access Dr. Raouf Khalil's publications, please click here.  

  • Helen Christou, MD, Newborn Medicine, Brigham and Women's Hospital
  • Toshio Kitazawa, PhD, Boston Biomedical Research Institute
  • Marco Lopez-Ilasaca, PhD, Department of Medicine, Brigham and Women's Hospital
  • Joseph D. Raffetto, MD, Staff Surgeon, VA Boston Healthcare System
  • Gordon H. Williams, MD, Department of Medicine, Brigham and Women's Hospital
Contact Information

Raouf A. Khalil, MD, PhD

Brigham and Women's Hospital
Division of Vascular Surgery
75 Francis Street Boston, MA 02115

Office Tel: 857-307-1920
Office 2 Tel: 617-525-8530
Lab Tel: 617-525-8531
Fax: 617-264-5124

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