Ozaki Lab
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Director, Vascular
Surgery Research |
Vice Chair,
Department of Surgery |
John A. Mannick Professor of Surgery, Professor of Surgery at Harvard Medical School |
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The Ozaki Basic Vascular Biology Laboratory of the Division of Vascular and Endovascular Surgery broadly aims to delineate the mechanisms by which physical forces alter the morphology of the blood vessel wall. The team holds expertise specifically in the adaptations of the vein bypass graft, an extreme example of acute perturbation of the hemodynamic environment combined with vascular trauma. Recent investigative efforts have focused on inflammatory driven mechanisms of these adaptations. Future research directions expand (in both animal models and humans) this foundation of knowledge via enhanced in vivo imaging of the blood vessel wall, investigations into links between adipose biology and vascular adaptations, and robust analyses of the longitudinal interplay between local hemodynamic factors and biochemical mediators.
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Celebrating the life of our Eternal Research Partner James Mitchell Ph.D. |
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Recent Funding |
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Publications |
- To access Dr. C. Keith Ozaki's publications, please click here.
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Collaborators |
- Masanori Aikawa, MD PhD, Cardiovascular Division, Brigham and Women's Hospital
- Scott A. Berceli, MD PhD, Division of Vascular Surgery, University of Florida
- Christopher Chen, MD, PhD, Biomedical Engineering, Boston University
- Yu Shrike Zhang, PhD,Bioengineer, Brigham and Women's Hospital/Harvard Medical Shool
- Glenn R. Gaudette, PhD, Dept of Biomedical Engineering, Worcester Polytechnic Institute
- Imo Hoefer, MD PhD, Lab of Experimental Cardiology, University Medical Center Utrecht
- Zhihua Jiang, MD PhD, Division of Vascular Surgery, University of Florida
- Jeffrey Karp, PhD, Harvard-MIT Division of Health Sciences and Technology
- Bruce S. Kristal, PhD, Department of Neurosurgery, Brigham and Women's Hospital
- Maria Pereira, PhD, Chief Innovation Officer at Tissium
- Peter Libby, MD, Cardiovascular Division, Brigham and Women's Hospital
- Frank W. LoGerfo, MD, Division of Vascular Surgery, Beth Israel Deaconess Medical Center
- Matthew D. Phaneuf, BS, President and CTO, BioSurfaces Inc.
- Paul H. A. Quax, PhD, Leiden University Medical Center, Leiden, Netherlands
- Karen Ho, MD PhD, Department of Surgery, Northwestern University Feinberg School of Medicine
- Lisa Molz, PhD, Senior Director of Translational Sciences at Mitobridge, An Astellas Company
- Margreet R. de Vries, PhD, Leiden University Medical Center, Leiden, Netherlands
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Contact Information |
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Ozaki Clinical Office
Vascular and Endovascular Surgery
Brigham and Women's Hospital / Harvard Medical School
75 Francis Street
Boston, MA 02115
Phone: 857-307-1920
Fax: 857-307-1922
E-mail: ckozaki@partners.org
Ozaki Vascular Surgery Research Lab
Thorn Building, Room 1031
20 Shattuck St.
Boston, MA 02115
Phone: 617-525-8529; 617-525-8528
Fax: 617-264-6863 |
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